This diagnostic course of makes use of laser-based know-how to research the bodily and chemical traits of blood, bone marrow, or lymph node cells. A focused assortment of antibodies, every tagged with a novel fluorescent dye, binds to particular proteins on the floor and inside these cells. The ensuing fluorescent indicators are measured and interpreted to determine cell populations, quantify their proportions, and characterize their options, equivalent to dimension, granularity, and protein expression. This information supplies essential insights into the presence and classification of hematologic malignancies.
Immunophenotyping by way of this technique is invaluable in diagnosing and managing numerous blood cancers. It permits for exact illness classification, guiding therapy methods and predicting prognosis. This superior method helps distinguish between several types of leukemia and lymphoma, determine particular subtypes, and detect minimal residual illness after therapy. Traditionally, microscopic examination of cells offered restricted data. The event and refinement of this know-how represents a big development, enabling clinicians to make extra knowledgeable choices based mostly on detailed mobile data.
